Free UK delivery for orders over £50
365 Day Returns
£20 off orders over £100 – code MAY20
Free UK delivery for orders over £50
365 Day Returns
£20 off orders over £100 – code MAY20
Free UK delivery for orders over £50
365 Day Returns
£20 off orders over £100 – code MAY20
Free UK delivery for orders over £50
365 Day Returns
£20 off orders over £100 – code MAY20
Free UK delivery for orders over £50
365 Day Returns
£20 off orders over £100 – code MAY20
Free UK delivery for orders over £50
365 Day Returns
£20 off orders over £100 – code MAY20
Free UK delivery for orders over £50
365 Day Returns
£20 off orders over £100 – code MAY20

Methyl-Guard optimises methylation for better heart, brain, and bone health with active, ready-to-use nutrients.

Size:

180 caps

£44.99
Free sample each month
Pause or cancel anytime
365 day free returns
In stock. Next day delivery available.

Buy now, pay later from £12.50/mo with

Free UK shipping over £50, free returns.
  • american-express
  • apple-pay
  • google-pay
  • master
  • paypal
  • visa

Key Benefits

  • Supports cardiovascular, cognitive, and bone health.
  • Helps maintain healthy homocysteine levels.
  • Provides active, tissue-ready nutrients for superior absorption and effectiveness.

Thorne’s Methyl-Guard is a comprehensive formula that combines betaine, 5-MTHF, methyl-B12, and P5P to support healthy methylation, crucial for cardiovascular, cognitive, and bone health. Methylation plays a vital role in maintaining healthy homocysteine levels, which is as essential to cardiovascular health as normal cholesterol and triglyceride levels. Proper methylation is not only key to regulating homocysteine but also supports neurotransmitter function, detoxification, eye health, muscle function, bone strength, and redox balance.

Given that many adults have impaired methylation due to a common genetic mutation affecting a key methylation enzyme, Methyl-Guard provides targeted support by offering nutrients in their active, tissue-ready forms. As the first nutritional supplement to support homocysteine metabolism and healthy methylation, Methyl-Guard remains a trusted choice for those looking to optimise their overall health and wellbeing.

Methyl-Guard addresses a critical biochemical process—methylation—that impacts everything from cardiovascular health to cognitive function and bone strength. Unlike standard supplements, Methyl-Guard provides nutrients in their active, tissue-ready forms, ensuring superior absorption and effectiveness. This is especially important for those who have a genetic mutation that impairs methylation. By supporting healthy homocysteine levels and offering comprehensive benefits across multiple systems, Methyl-Guard provides a more targeted, effective, and holistic approach to maintaining overall wellbeing.

Thorne sets the standard for excellence in the supplement industry. Recommended by over 100 professional sports teams and U.S. National Teams, Thorne offers a curated bundle of clean, science-backed supplements and treats designed to fuel your body naturally and effectively. With more than 30 years of dedication to quality, Thorne's commitment to purity and potency begins with sustainably sourced ingredients and rigorous testing. Every supplement undergoes four rounds of testing to ensure optimal absorption, safety, and efficacy, making Thorne the trusted choice for both health-conscious individuals and professionals.

With our Healf Curation Process, we do the work for you. Shop with confidence knowing that every item has been tried, tested, and curated for you.

Learn more about each step—Brand Discovery, Expert Validation, and Community Testing—here.

Betaine Anhydrous (Trimethylglycine), Folate (L-5-MTHF), Vitamin B12 (Methylcobalamin), Vitamin B6 (Pyridoxal 5'-Phosphate). Other Ingredients: Calcium (Citrate), Calcium Laurate, Hypromellose Capsule, Silicon Dioxide.

Shipping

At Healf, we prioritize safe and fast delivery for all our customers. Our carefully selected couriers are Royal Mail and DPD.

UK standard delivery

Enjoy free standard delivery on orders above £50, this option usually requires 2-3 working days. If your order is under £50, this delivery option is available for £3.99.

Next working day

For when you need our products urgently, we offer next working day shipping for £5.99. For orders placed before 12.00, we will ship it the same day to ensure you receive your order the next working day.

International

International deliveries can take 7 working days, and up to 4 weeks. The cost is £22.99 for orders below £50, £49.95 for orders above.

Returns

If for any reason you are not satisfied with your order, we provide free 365-day UK returns for all our customers. To initiate your return, simply contact us at team@healf.com, and we'll send you a return slip and help arrange a collection. The item you return must be sent in the same condition as received and inside the original packaging. Once received, we will notify you via email.

For international returns, we unfortunately do not cover the cost. However, we work with an array of carriers and can offer self-posting returns for customers shopping from outside the UK.

Take three capsules twice daily or as recommended by your healthcare professional.

You may also like

Shop by collection

Frequently asked questions

Every product undergoes our Healf Curation Process. With it, you can shop confidently knowing that every item has been tried and tested before it reaches you. Our Healf Curation Process includes three key steps: Brand Discovery, Expert Validation, and Community Testing. Through these, we assess quality, ingredients, effectiveness, and more, ensuring that every product empowers your wellbeing.

The Healf Journal offers detailed insights into different aspects of wellbeing, as well as guidance, research, recipes, and more to help you invest in your personal wellbeing journey. You can also subscribe to our weekly newsletters for the latest updates at Healf and in the wellbeing industry. Subscribe via the sign-up block at the bottom of this page.

We love people who check ingredients as carefully as we do, so you'll find detailed information about the ingredients used on every product page (where applicable). If you see something you'd like to flag with us or have additional questions, please don't hesitate to get in touch—we'd love to hear from you.

Go to FAQs
Healf Zone Banner
New

Translate your body’s data
into a personalised
wellbeing plan.

Learn more

Healf Curation
Process™

Every product undergoes our rigorous Healf Curation Process, ensuring you are always getting the best when it comes to your wellbeing.

Discover more
Go to Page

The Discovery

pointer

Our approach keeps us at the forefront of wellbeing. With our global network of health professionals and AI-powered trend analysis, we curate the leading supplements, tools, and tech that pioneer the industry.

Go to Page

Expert Validation

pointer

Each product at Healf is carefully examined by a panel of industry specialists—including dieticians, personal trainers, psychologists, and sleep experts—to ensure it meets our high standards for quality, efficacy, and ingredient formulations.

Go to Page

Community Testing

pointer

By collaborating with a dedicated group of customers who test and review each product, we ensure that only those truly beneficial to your wellbeing are offered here at Healf.